Structure Modification and Antifertility Activity of Anordrin Analogues;
双炔失碳酯类似物的结构修饰及抗生育活性
Objective: To find anordrin analogs possessing higher bioactivity and lower side effect after reconstructing anordrin.
目的:通过改造双炔失碳酯的化学结构,获得活性更高、副作用更小的避孕药。
Results: Anordrin inhibited the production of hCG、E 2、P and stimulated the synthesis of PGF 2α in chorionic and/or decidual tissue cells in vitro( P<0.
本实验以绒毛、蜕膜组织细胞培养为模型 ,用放射免疫测定方法 ,观察了双炔失碳酯对绒毛、蜕膜组织细胞分泌功能的影响。
Methods: A-nor-steroidal-17-carbonyl-5α-steranes-2α-acetylene-2β-hydroxy as raw materials, through the struc- tural modification, anordiol analogues were synthesized.
方法:以化合物A环失碳-17-羰基-5α-雄甾烷-2α乙炔基-2β-羟基为原料,通过对双炔失碳醇进行结构修饰,经数步反应得到各种含N或S基团的α-双炔失碳醇类似物,并对获得的新化合物进行体外黄体细胞抑制活性的生物试验。
Effect of α-anordrin on the growth of transplanted tumor of prostate cancer cell LNCaP in nude mice;
α-双炔失碳酯对前列腺癌LNCaP裸鼠移植瘤生长影响的研究
The Effects of α-anordrin on Androgen-dependent Human Prostatic Cell Lines LNCaP;
α-双炔失碳酯抗雄激素依赖型人前列腺癌细胞LNCaP的实验研究
Determination of Carbyne Content with the Ratio of IR Peak Intensity;
谱峰相对强度比法在碳炔含量测定中应用
Theory Simulation of Infrared Spectra of Carbyne;
碳炔分子红外振动光谱的理论模拟研究
Comparison of the Different Effects between Two Epimerides of Anordrin α and β Monomer on Human Prostatic Cancer in Vitro
双炔失碳酯α、β单体体外抗前列腺癌作用比较
The Effects of α-anordrin on Androgen-dependent Human Prostatic Cell Lines LNCaP;
α-双炔失碳酯抗雄激素依赖型人前列腺癌细胞LNCaP的实验研究
Anti-prostate Cancer Activity of α-anordrin and Its Inhibition Effects on Sex Glands Growth and Testosterone Secretion of Male SD Rat;
α-双炔失碳酯抗前列腺癌作用及对雄性大鼠性器官生长和性激素分泌的影响
Effects of Mifepristone Combined with Anordrin or Tamoxifen on the Endocrine Function of Chorion and Decidua in Early Human Pregancy;
米非司酮与双炔失碳脂或三苯氧胺合用对人早孕绒毛、蜕膜内分泌功能的影响
Synthesis 1,4-bis[β-(p-phthalic anhydride)ethynyl]benzene via C-C coupling reaction
碳-碳偶合反应合成1,4-双[β-(p-邻苯二甲酸酐)乙炔基]苯
Study of Solid State Polymerization of Bis (p-Toluene Sulfonate)of 2,4-Hexadiyne-1,6-Diol with Laser Micrometry
激光测微法研究双(对甲苯磺酸)-2,4-已二炔-1,6-二醇酯的固态热聚合
Synthesis and Optical Properties of Liquid Crystalline Polyacetylene Containing Bis(4-alkylphenyl)terephthalate as Pendant;
含对苯二甲酸双烷基苯酯侧链液晶聚乙炔的合成及其光学性能
Study on the Synthesis of Bisphenol-A Co-Polycarbonate with Reduced Birefringence Through Melt Transesterification Process;
熔融酯交换法合成低双折射共聚碳酸酯的研究
A molecular dynamics simulation of the plastic behavior of bis-phenol-A-polycarbonate
双酚A型聚碳酸酯形变行为的MD模拟
Three Phosgene Instead of Bisphnol S/Bisphnol A Carbonic Acid Polyester which Composed by Phosgene
三光气替代光气合成双酚S/双酚A型聚碳酸酯
The Synthesis and Characterization of Bisphenol-A Polycarbonate with Triphosgene;
三光气法双酚A型聚碳酸酯的合成与表征
The Supply and Demand of Polycarbonate and its Stock Diphenol A as well as Technology Progress;
聚碳酸酯及其原料双酚A的供需和技术进展
Advances in Studies on the Synthesis and Properties of Bisphenol-A Polycarbonate
双酚A型聚碳酸酯的合成与性能研究进展
Determination of bisphenol A in polysacchairde for food packing materirals
食品包装材料聚碳酸酯中双酚A残留量的测定
Study on Lead-Zinc Double Oxide Deactivation and Supported Liquid Phase Catalysts in Synthesis of Diphenyl Carbonate by Transesterification;
酯交换法合成碳酸二苯酯催化剂失活和负载液相催化剂的研究
Study on the Chronic Oral Toxicity of 50.5 Percent C_(17)H_(22)N_(2O4);
50.5%炔咪菊酯母液慢性经口毒性实验
Preparation of Carbon Nanofibers by Catalytic Pyrolysis Ethine using Cu/La_2O_3 as the Catalyst
Cu/La_2O_3催化裂解乙炔制备碳纳米纤维
Inhibition Effect of Propiolic alcohol on Mild Steel in Mud Acid
土酸溶液中丙炔醇对碳钢的缓蚀作用
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