The permeabilization of free whole cell was also observed, and it had a relationship with the change of \{microstructure\} of cell membrane.
对游离整体细胞（大肠杆菌）的生物转化行为，特别是在高质量浓度底物（富马酸铵）环境下的细胞形态结构进行考察，解释了高质量浓度底物，反应行为，细胞结构和细胞渗透化之间的关系。