Construct the monovalent vaccine pVAX1/SjHGPRT、pVAX1/ SjSDISP and the multivalent vaccine pVAX1/SjHGPRT·SDISP which is the target gene against Schistosoma japonicum.
研究目的1、针对抗日本血吸虫生殖产卵编码基因SjHGPRT、SjSDISP,构建单价疫苗pVAX1/SjHGPRT、pVAX1/SjSDISP及多价疫苗pVAX1/SjHGPRT·SDISP,并获得良好的表达;2、观察并比较单价疫苗pVAX1/SjHGPRT、pVAX1/SjSDISP和多价疫苗pVAX1/SjHGPRT·SDISP免疫小鼠产生的保护力。
The SPF chickens were inoculated at 1 day old by cervix subcutaneous with 25 000 PFU trivalent vaccine per chicken.
将MD三价疫苗以25 000 PFU/只的剂量颈部皮下接种1日龄SPF雏鸡,结果表明,疫苗的接种不影响鸡体重的增加;不引起鸡法氏囊、脾脏等组织器官发生MD组织病理学变化,对鸡安全无毒性。
Establishment of B16-HLA-MAGE-3 melanoma cell line coexpressing HLA-A*0201/K~b and MAGE-3 and its role in tumor vaccine evaluation;
HLA-A*0201/K~b及MAGE-3基因共转染B16细胞的制备及其在MAGE-3肿瘤疫苗评价中的作用
Study on a Multivalent Live Oral Vaccine Against Human Enterotoxigenic Escherichia Coli;
肠毒素大肠杆菌口服多价疫苗的研究
Construction and Immunogenicity of a Multistage, Multivalent Vaccine against Falciparum Malaria;
恶性疟疾多期多价疫苗的构建及免疫原性的研究
Random Amplified Polymorphic DNA of Swine Streptococcus Suis and Research of Polyvalent Inactivated Vaccine;
猪链球菌随机扩增多态性DNA分析及多价疫苗研制
Research on the combine nucleic acid vaccine and immunity of Canine
犬联合多价核酸疫苗的实验免疫研究
Influenza may be prevented by active immunization with a polyvalent killed or subunit vaccine.
可以通过主动免疫接种多价灭活疫苗或亚单位疫苗预防流感。
An Experimental Study on the Polyvalent DNA Vaccine Against C.Jejuni;
空肠弯曲菌多价DNA疫苗的实验研究
Construction of the Multivalent DNA Vaccine of Mycobacterium Tuberculosis HSP65 and Cytokine IL-12 and its Identification
结核杆菌HSP65与IL-12多价DNA疫苗的构建
Evaluation of Porous Microsphere Vaccine Containing rV270 Antigen Against Yersinia pestis Challenge
基于rV270抗原的鼠疫多孔微球疫苗的制备及其免疫保护作用评价
Molecular design and immunogenicity of a multiple-epitope foot-and-mouth disease virus antigen,adjuvants,and DNA vaccination
口蹄疫病毒三价复合多表位佐剂DNA疫苗构建及其免疫原性
Study on the Mucosal Immunity of Multi-Stage and Multi-Epitope DNA Vaccine Against Toxoplasma Gondii;
弓形虫多价和多表位核酸疫苗黏膜免疫的实验研究
Experimental Study on Helicobacter Pylori Polyvalent Oral Recombinant DNA Vaccine;
幽门螺杆菌多价口服核酸疫苗实验研究
DNA Vaccines Against Mycobacterium Tuberculosis and Brucella Abortus;
结核杆菌和布鲁氏杆菌多价DNA疫苗的研究
Construction of Vaccinia Virus Vector Expressing HIV-1 Poly-valent Synthetic Gene and Screening of Recombinant Vaccinia Virus for Vaccine;
表达HIV-1多价合成基因的痘苗病毒载体构建及疫苗株筛选
The test proved that the polyvalent inactivity vaccine is safe and effective.
试验证明,该多价灭活疫苗安全性好,免疫效果确实。
Generation and Immunological Characterization of Recombinant Fowlpox Viruses Expressing Immunogens of Other Avian Viruses;
表达多种外源基因的鸡痘病毒载体疫苗构建及免疫学评价
Valuation of theoretical immune response status of HBV multi-epitope vaccines in existence in the population of China
现有乙型肝炎多表位疫苗在中国人群中的理论免疫效果评价
Construction and immunoprotection of Schistosoma japonicum multivalent DNA vaccine in mice
日本血吸虫多价核酸疫苗的构建及免疫保护试验
Perfection of Vaccine Pricing Policy through research on Vaccine price-relating attributes
从疫苗价格相关属性谈疫苗定价政策的完善
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