Objective To observe the effect of chronic unpredicted sequence of mild stress on the expression of cAMP-dependent protein kinase A(PKA) and phosphorylated cAMP-responsive element binding protein (P-CREB) in hippocampus of rats and the antagonism of antidepressors (fluoxetine).
目的:探讨慢性轻度不可预见应激对大鼠海马神经元内环磷酸腺苷依赖性蛋白激酶A(cAMP-dependentproteinkinaseA,PKA)和磷酸化的环磷酸腺苷反应元件结合蛋白(phosphorylatedcAMP-responsiveelementbindingprotein,P-CREB)表达的影响以及抗抑郁剂(氟西汀)的拮抗作用。
Role of cGMP-dependent protein kinase against ethanol neurotoxicity of cerebellar granule cells;
环鸟苷酸依赖性蛋白激酶拮抗酒精性中枢神经细胞毒性机制研究