It is also expected to construct a platform for therapeutic antibody humanization including gene modification, construction of expressing vector, st
基于本实验室近期构建的一个具有血凝抑制(AI)活性的H5特异性单克隆抗体库(已经用41株包含全部10个遗传进化分支的H5N1病毒代表株对这些单抗的HI活性和以小鼠为动物模型的中和活性进行了测定),本研究选取四株广谱中和活性强的鼠单抗:4D1、10F7、8H5、13D4进行人源化改造,以降低鼠抗在人治疗过程中的HAMA反应,为这些抗体尽快进入临床应用奠定基础;同时也希望建立一套治疗性抗体人源化研究的平台体系,包括基因的改造、表达载体的构建、哺乳动物细胞高效稳定表达、无血清大规模培养、抗体纯化工艺等。
Hybridom techniques have made mouse monoclonal antibody widely use in diagnosis and research of human disease, and established the first milestone of therapeutic antibody.
杂交瘤技术使鼠源单克隆抗体(鼠单抗)被广泛用于人类疾病的诊断和研究,建立了治疗性抗体的第一个里程碑。
Substantive Due Process of American Constitution for Protection the Right to Refuse Life-sustaining Treatment;
美国宪法实体性正当程序对拒绝治疗权的保护
If a woman is denied treatment on the grounds that she could not possibly benefit, the basis of that denial had better be rock-solid.
如果一名女性以不太可能从治疗中获利的理由而被拒绝治疗,其理论根据最好坚如磐石。
Some participants at the meeting hold that euthanAsia can be resorted to in case a patient refuses treatment and is inevitably dying
部分与会者认为,对于本人拒绝治疗且又显然无法救治的病人可以考虑采取安乐死
In May,she became very ill and refused to be admitted to a hospital.
五月,她病情恶化,但拒绝前往医院治疗。
By the pathologic study from the liver biopsy, it confirmed the diagnosis of bile duct hamartoma.
但病人拒绝手术治疗,而改在门诊定期追踪。
It was the time to remedy the enormous sadness.
她拒绝承认失败,这正是治疗巨大伤痛的时刻。
You can receive or refuse the suggested checkup and ways of treatments from your doctor.
可以接受或拒绝医师建议的检查、治疗方式。
Impact of Different Treatment Methods of School Refusal Among Adolescents;
不同治疗方法对儿童青少年拒绝上学的疗效观察
Some refused to see doctors when ill and subsequently died when it was too late for medical treatment.
有些人被欺骗迷惑后,患病拒绝就医,贻误治疗,导致死亡。
The court refused to extradite political refugees.
法庭拒绝引渡政治避难者。
He refused to give an opinion on the political situation.
他拒绝对政治形势发表意见。
George Wash-ington turned down the offer of a kingship and chose the presidency instead.
乔治·华盛顿拒绝王冠而选择了总统。
George Mason refused to sign the Constitution.
乔治?梅森拒绝在宪法上签名。
refuse to pay a levy to a union for political use.
拒绝向用于政治的团体交纳税金。
A: The British denied the colonists self-government.
答:英国拒绝让殖民者拥有自治权。
To declare(a bill) dishonored or refused.
拒绝支付宣布(票据)拒受或拒绝
If intervention puts an end to disturbances and brings about order, should we welcome or reject it?
由乱变治,这样的干预应该欢迎还是应该拒绝?
The goverment refused to make any appraisement of the recent politics scandal.
政府拒绝对最近的政治丑闻作任何评价。
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